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A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression

In line, an imbalance favoring Th17 cells over regulatory T cells (Tregs) has been implicated in the progression of NAFLD in mice fed a HFD [67]

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[DOI] [PubMed] [Google Scholar] 13.Posadas I, Santos P, Blanco A, Muoz-Fernndez M, Cea V

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